In a recent study published in Nature Communications, researchers examine the effect of infection and coronavirus disease 2019 (COVID-19) vaccination in healthy individuals with diverse imprinted immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Previous immunity shapes immune responses to SARS-CoV-2 booster vaccination and Omicron breakthrough infection risk. Image Credit: Kateryna Kon / Shutterstock.com Background